Vol. 1, Issue 1, Part A (2019)

Abstract: Introduction: Deep penetrating nevus (DPN), also known as the plexiform spindle cell nevus, is a distinct variant of melanocytic nevus occurs as a pigmented lesion that exhibits deep infiltration into the reticular dermis and remains a histopathologic challenge to pathologists because of its resemblance to malignant melanoma and other benign lesions. It often goes unrecognized due to its relative rarity. Case presentation: Here we report a case of DPN of vulvar in an 11-year-old Moroccan girl. A brief review of the literature shows that histologically it can be differentiated from other entities, including malignant melanoma. Conclusion: DPN can be misdiagnosed as malignant melanoma, hence the importance of recognizing its clinical, epidemiological and especially histological characteristics.