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International Journal of Dermatology Research

Vol. 3, Issue 1, Part A (2021)

Methacillin resistant staphylococcus aureus (MRSA) in superficial bacterial skin infections

Author(s):

Mona M Alzeyani, Ghada A Albarghati, Gamal A Duweb

Abstract:
Background: Methacillin resistant staphylococcus aureus (MRSA) is any strain of staphylococci that has resistance to beta lactam antibiotics including the penicillins (methicillin, dicloxacillin, nafcillin, oxacillin, etc). Our aim in this study is assess methacillin resistant staphylococcus aureus among (MRSA) Libyan patients with superficial skin bacterial infections, to screen patients with MRSA skin infections for staphylococcus aureus nasal carriage. Patients and Methods: The study include 151 Libyan patients attending OPD clinic of dermatology department - Jomhoria hospital - Benghazi – Libya with the clinical diagnosis of superficial skin bacterial. All the patients were exposed to detailed disease history and complete dermatological examination according to the prepared proforma. Samples were taken from patient nares and infection sites and send directly to microbiology laboratory for detection of organisms. Oxacillin disc and other different antibiotic discs were fixed on Muller Hinton agar and incubated at 37c for 24-48hr (Disk diffusion test) according to the guidelines of the clinical and laboratory standards institute (CLSI). Results: Out of 151studed patients, 72 patients (47.7%) were males and 79 patients (52.3 %) were females with mean (25.9 years). Regarding the age groups, the highest percentage of patients was seen in age group 0-10 years and (28.5 %) of cases followed by age group 11-20 years and 21-30 years. Lower and upper extremities were involved in 29.1% and 17.9% respectively followed by the face and seen in 13% of the patients. Regarding the clinical diagnosis, furuncle (boil) was seen in 31 patients (20.5 %) followed by impetigo in 20 patients (13.2%), eczema with secondary bacterial infection in 16 patients (10.6), Approximately 70.9% of patients were not received antibiotics in last 12 months. Positive pus cultures were found in 82.1% of patients. Staphylococcus aureus was isolated from 77.4% of patients followed by streptococcus pyogenes. Regarding swab cultures of nasal area for carrier, 116 patients (76.8%) were had positive cultures. In 97 patients (83.6%), the type of bacteria in nasal swab culture was staphylococcus aureus followed by staphylococcus albus and constitute 8.6%. Out of the staphylococcus aureus isolates examined from infection site, 40.7% were methacillin resistant staphylococcus aureus (MRSA) and approximately 59 % of them were staphylococcus aureus nasal carriage. Conclusions: Superficial bacterial skin infections constitutes a major health problem in Benghazi – Libya and majority of patients affected by these diseases was aged ≤ 30 years. Resistance of staphylococcus aureus to methacillin was seen in 40.6 % whereas sensitivity was high to amikacin and clindamycin.

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International Journal of Dermatology Research
How to cite this article:
Mona M Alzeyani, Ghada A Albarghati, Gamal A Duweb. Methacillin resistant staphylococcus aureus (MRSA) in superficial bacterial skin infections. Int. J. Dermatol. Res. 2021;3(1):01-05. DOI: 10.33545/26646471.2021.v3.i1a.30