Vol. 7, Issue 1, Part B (2025)

The present study report the efficacy of a herbal preparation in arresting testosterone binding on hair root in-vitro and having effect in inhibiting alpha reductase enzyme. Alpha reductase enzyme arrest the conversion of testosterone and thereby DHT lead inactivation hair root is hindered. But our finding clearly show the formulation we tested not only has DHT conversion inhibition but also has effect on direct interaction between testosterone and hair root and binding of the same over hair root. The present findings show the possible usefulness of the formulation in addressing the problem of androgenic alopecia in lieu of finasteride which has serious safety concern.